Robert De Niro Frank Sheeran Al Pacino Jimmy Hoffa Joe Pesci Russell Bufalino Stephen Graham Anthony 'Tony Pro' Provenzano Ray Romano Bill Bufalino Harvey Keitel Angelo Bruno Bobby Cannavale 'Skinny Razor' Anna Paquin Older Peggy Sheeran Stephanie Kurtzuba Irene Sheeran Kathrine Narducci Carrie Bufalino Welker White Josephine 'Jo' Hoffa Jesse Plemons Chuckie O'Brien Jack Huston Robert Kennedy - RFK Domenick Lombardozzi 'Fat Tony' Salerno Paul Herman 'Whispers' DiTullio Louis Cancelmi 'Sally Bugs' Gary Basaraba Frank 'Fitz' Fitzsimmons Marin Ireland Older Dolores Sheeran Sebastian Maniscalco 'Crazy Joe' Gallo Steven Van Zandt Jerry Vale Lucy Gallina Young Peggy Sheeran Dascha Polanco Nurse Bo Dietl Joe Glimco Aleksa Palladino Mary Sheeran Daniel Jenkins E. Howard 'Big Ears' Hunt Jim Norton Don Rickles Billy Smith FBI Agent #1 Action Bronson Casket Salesman Paul Ben-Victor Jake Gottlieb Barry Primus Ewing King J. C. MacKenzie Prosecutor Jim Neal John Cenatiempo Anthony 'Tony 3 Fingers' Castellito Garry Pastore Albert Anastasia Lawrence Smith Louis Rebecca Faulkenberry Barbara Hoffa Matthew F. O'Connor Pro Rally Teamster #1 Clark Carmichael Pilot Fidel Castro Himself (archive footage)