Isabela Merced Dora Jeffrey Wahlberg Diego Madeleine Madden Sammy Eugenio Derbez Alejandro Gutierrez Michael Peña Cole - Dora's Father Eva Longoria Elena Benicio del Toro Swiper (voice) Madelyn Miranda Dora (6 years) Malachi Barton Diego (6 years) Dee Bradley Baker Animal Vocalizations (voice) Sasha Toro Backpack (voice) Marc Weiner Map (voice) Joey Vieira Nico Pia Miller Sabrina - Diego's Mother Adriana Barraza Abuela Valerie Damien Garvey Security Guard Nicholas Coombe Randy Tivon Toito'ona Soccer Team Kid 1 Emily Bell Soccer Team Kid 4 Christopher Kirby Viper Danny Trejo Boots (voice) Q'orianka Kilcher Kawillaka Caleb McLaughlin Tico (voice)