Joaquin Phoenix Beau Wassermann Patti LuPone Mona Wassermann Amy Ryan Grace Parker Posey Elaine Bray Nathan Lane Roger Armen Nahapetian Teen Beau Stephen McKinley Henderson Beau's Therapist Richard Kind Dr. Cohen Kylie Rogers Toni Denis Ménochet Jeeves Zoe Lister-Jones Young Mona Julia Antonelli Teen Elaine Hayley Squires Penelope Julian Richings Strange Man Bill Hader UPS Guy Alicia Rosario Liz Catherine Bérubé Hero Beau's Wife Stephanie Herrera Martha Bradley Fisher Birthday Boy Stab Man Michael Esper Officer Johnson Manuel Tadros Cheapo Depot Cashier Cat Lemieux Orphan Chorus Member #2 Tristan D. Lalla Costume Designer Orphan Tyrone Benskin Rattled Businessman Archie Madekwe Laughing Man Luis Oliva Crust Punk (Eyes Gouged) Marie-Michelle Garon Fraught Mother Looking for Boat Boy Maev Beaty Angel / Narrator Patrick Kwok-Choon Orphan Hero Michael Gandolfini Beau’s Son Théodore Pellerin Beau’s Son Mike Taylor Beau’s Son Bentley Hughes Hero Beau's Young Son Kwasi Songui Orphan Ladybug Man Cat Lemieux Orphan Chorus Member Arthur Holden Duncan / God on Cloud / Hero Beau’s Wife